Evidence map›Paper›PMID 42576101›Full record

ArticleClinical oral investigations2026

Soft-tissue thickness changes following bimaxillary surgery in skeletal class II malocclusion.

Hao Chen, Dirk-Melle Beek, Frank Baan, Stephan Christian Möhlhenrich, Kasper Stokbro, Tong Xi

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Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Hao ChenDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Huangsha Avenue 39, Liwan District, Guangzhou, Guangdong, 510150, China.
Dirk-Melle BeekDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, PO Box 9101, Nijmegen, 6500, the Netherlands.
Frank BaanRadboudumc 3D Lab, Radboud University Medical Center, Geert Grooteplein 10, Nijmegen, HB, 6500, Netherlands.
Stephan Christian MöhlhenrichDepartment of Dentistry, Section of Orthodontics, Dentofacial Orthopedics and Craniofacial Biology, Radboud University Medical Center, P.O. Box 910, 309, Nijmegen, HB, 6500, The Netherlands.
Kasper StokbroDepartment of Oral and Maxillofacial Surgery, Odense University Hospital, Sdr. Boulevard 29, Odense, 5000, Denmark.
Tong XiDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, PO Box 9101, Nijmegen, 6500, the Netherlands. Tong.Xi@radboudumc.nl.ORCID https://orcid.org/0000-0002-9142-9253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis retrospective cohort study evaluated regional facial soft-tissue thickness changes after bimaxillary surgery in skeletal Class Ⅱ patients and assessed their associations with skeletal movement and patient-related factors. MATERIALS AND

methodsClass Ⅱ patients treated with bimaxillary advancement surgery without genioplasty were included. Postoperative CBCT scans, acquired 16.7 ± 5.3 months after surgery, were registered to the corresponding preoperative scans using voxel-based superimposition. Skeletal displacement and corresponding overlying soft-tissue thickness were assessed at subspinale (A), supradentale (Sd), infradentale (Id), supramentale (B), pogonion (Pog), and menton (Me). Soft-tissue thickness was defined as the linear distance between each hard-tissue landmark and its corresponding soft-tissue landmark. Skeletal displacement was measured at the corresponding hard-tissue landmarks.

results89 patients were enrolled, 33 male and 56 female, mean age of 30.3 ± 10.3 years. Significant postoperative soft-tissue thinning was observed at A (0.40 ± 1.51 mm), Id (2.20 ± 2.11 mm), B (0.33 ± 1.30 mm), and Pog (0.48 ± 1.29 mm), whereas soft-tissue thickness at Sd and Me did not change significantly. Pearson correlation analysis indicated that thickness changes were not associated with age, sex, or CBCT interval. Larger sagittal advancement at A and Id was associated with more pronounced thinning of the corresponding soft tissue (A: r = -0.650, p < 0.001; Id: r = -0.338, p = 0.001), with ratios of thinning to movement of 0.20 and 0.30, respectively. In contrast, larger downward vertical movement of B was associated with less thinning at B (r = 0.240, p = 0.023), with a ratio of thinning to downward movement of 0.05.

conclusionBimaxillary surgery in skeletal Class II patients without genioplasty resulted in region specific soft-tissue thinning, particularly affecting the lower lip. CLINICAL RELEVANCE: Postoperative soft-tissue thinning should be considered during surgical planning and patient communication.

Indexed as

FaceMalocclusion, Angle Class IIMaxillaAdultCone-Beam Computed TomographyFemaleHumansMaleRetrospective StudiesTreatment OutcomeCone-beam computed tomographyFacial esthetics.Malocclusion, Angle class IIOrthognathic surgerySoft-tissue thickness

Identifiers

PMID42576101
PMCPMC13457495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.