Evidence map›Paper›PMID 42576100›Full record

ReviewSkeletal radiology2026

Challenging bone biopsies: what radiologists needs to know.

Leonor Garbin Savarese, Nicolas Papalexis, Mateus de Andrade Hernandes, Paolo Spinnato, Giancarlo Facchini, Marco Miceli, Nelson Fabricio Gava, Edgard Eduard Engel, Marcello Henrique Nogueira-Barbosa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leonor Garbin SavareseDepartment of Medical Imaging, Hematology and Clinical Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900 CEP, Ribeirão Preto, São Paulo, 14049-090, Brazil. lsavarese@hcrp.usp.br.ORCID http://orcid.org/0000-0002-1372-9162
Nicolas PapalexisDepartment of Radiology, ARNAS G. Brotzu - Businco Oncologic Hospital, Cagliari, Italy.
Mateus de Andrade HernandesDepartment of Medical Imaging, Hematology and Clinical Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900 CEP, Ribeirão Preto, São Paulo, 14049-090, Brazil.
Paolo SpinnatoDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Giancarlo FacchiniDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Marco MiceliDiagnostic and Interventional Radiology Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Nelson Fabricio GavaDepartment of Orthopedics and Anesthesiology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Edgard Eduard EngelDepartment of Orthopedics and Anesthesiology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, São Paulo, Brazil.
Marcello Henrique Nogueira-BarbosaDepartment of Medical Imaging, Hematology and Clinical Oncology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900 CEP, Ribeirão Preto, São Paulo, 14049-090, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone biopsies play a pivotal role in the diagnostic workup of a wide range of bone pathologies. In many cases, image-guided percutaneous biopsy is favored over surgical approaches because it is minimally invasive, highly accurate, cost-efficient, and associated with lower morbidity. Among the available imaging modalities, CT guidance offers superior spatial resolution and enables precise needle placement, but certain skeletal locations remain technically demanding even under CT guidance. This review focuses on challenging CT-guided bone biopsy scenarios, including lesions adjacent to critical neurovascular or spinal structures, densely sclerotic lesions, and lesions occult on CT, and illustrates practical decision-making through representative clinical cases.

Indexed as

BiopsyBone diseasesBone neoplasmsInterventionalNeedleRadiologyTomography

Identifiers

PMID42576100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.