Evidence map›Paper›PMID 42576077›Full record

ArticleSurgical endoscopy2026

Clinical utility of single-balloon enteroscopy for malignant small bowel tumors.

Jiro Kawashima, Shin-Ei Kudo, Noriyuki Ogata, Yasuharu Maeda, Keisuke Sasabe, Yurie Kawabata, Takanori Kuroki, Yosuke Minegishi, Taishi Okumura, Yuta Kouyama and 8 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jiro KawashimaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Shin-Ei KudoDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Noriyuki OgataDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan. n.ogata@med.showa-u.ac.jp.ORCID http://orcid.org/0000-0001-6407-9422
Yasuharu MaedaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Keisuke SasabeDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Yurie KawabataDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Takanori KurokiDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Yosuke MinegishiDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Taishi OkumuraDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Yuta KouyamaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Tatsuya SakuraiDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Kenta NakaharaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Katsuro IchimasaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Masashi MisawaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Takemasa HayashiDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Naruhiko SawadaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.
Toshiyuki Baba
Kazuo OhtsukaDigestive Disease Center, Showa Medical University Northern Yokohama Hospital, 35-1, Tsuzuki, Yokohama, Kanagawa, 224-8503, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate pre-treatment characterization of small bowel tumors (SBTs) is essential because therapeutic strategies differ markedly by pathology. Although single-balloon enteroscopy (SBE) enables direct visualization, localization, and biopsy, its clinical utility for treatment planning in malignant SBTs remains insufficiently characterized.

methodsThis retrospective single-center study included patients who underwent SBE for suspected SBTs between September 2005 and July 2024, excluding hereditary polyposis syndromes. The analysis was restricted to malignant lesions; therefore, diagnostic-performance indices were not estimated. Outcomes were establishment of an SBE-derived pre-treatment diagnosis, concordance among these lesions, lesion reach rate, biopsy yield, tattooing rate, and avoidance of surgery required for diagnosis.

resultsAmong 1407 SBE examinations in 1089 patients, 86 malignant lesions in 85 patients were analyzed. The most common indication was obscure gastrointestinal bleeding (36.0%). Malignant lymphoma was most frequent (40.7%), followed by adenocarcinoma (22.1%), gastrointestinal stromal tumor (18.6%), and metastatic carcinoma (12.8%). The target lesion was reached in 84.9% (73/86). An SBE-derived pre-treatment diagnosis was established in 75.6% (65/86), with 95.4% (62/65) concordance with the final diagnosis. Biopsy yielded pathological confirmation in 92.9% (52/56); the intention-to-diagnose yield was 60.5% (52/86). Tattooing was performed in 65.6% (40/61) of treated lesions overall and 83.3% (40/48) of reached treated lesions. Diagnostic surgery was avoided in 75.6% (65/86) of lesions overall and 82.9% (29/35) of malignant lymphoma lesions.

conclusionsIn this malignant SBT cohort, SBE provided clinically useful information for lesion localization, histological confirmation, and treatment planning. Diagnostic surgery was avoided in 75.6% of lesions; however, this descriptive workflow finding should not be interpreted as a demonstrated causal effect of SBE.

Indexed as

BiopsyMalignant lymphomaSingle-balloon enteroscopySmall bowel tumorSurgical avoidance

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.