Evidence map›Paper›PMID 42576071›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Predictive value of [

Grace Keane, J Chalaye, B Guiu, L Tselikas, K D Fowers, E Boucher, E Garin, X Palard, M G E H Lam

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Grace KeaneDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, 3508 GA, The Netherlands. g.e.m.keane@umcutrecht.nl.ORCID http://orcid.org/0009-0003-9426-6626
J ChalayeAssistance Publique Hôpitaux de Paris, Paris, France.
B GuiuDepartment of Radiology, St-Eloi University Hospital, Montpellier, France.
L TselikasDépartement d'Anesthésie Chirurgie et Interventionnel, Interventional Radiology unit, Gustave Roussy Université Paris Saclay, Villejuif, France.
K D FowersBoston Scientific Corporation, Marlborough, MA, USA.
E BoucherBoston Scientific Corporation, Marlborough, MA, USA.
E GarinDepartment of Nuclear Medicine, Centre de Lutte Contre le Cancer Eugène Marquis, Rennes, France.
X PalardDepartment of Nuclear Medicine, Centre de Lutte Contre le Cancer Eugène Marquis, Rennes, France.
M G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht, 3508 GA, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe DOSISPHERE-01 study demonstrated a survival benefit for patients treated with MATERIALS AND

methodsAll DOSISPHERE-01 patients with both pre-treatment [

resultsThirty-seven patients were included: 19 from the personalised arm and 18 from the standard dosimetry arm. Pre- and post-treatment absorbed dose differences were not statistically significant for the index lesion (241 Gy vs. 229 Gy, p = 0.15; mean difference 11.9 Gy; 95% LoA - 84.3 to 108.2 Gy), Perfused Volume Normal Liver Tissue (PVNT) (91 Gy vs. 99 Gy, p = 0.14; mean difference - 8.2 Gy; 95% LoA - 71.6 to 55.1 Gy), or DVH metrics (V200, D70, D50) using anatomic segmentation. Corresponding metrics were significantly different using count-threshold segmentation (p < 0.05). For both methods, pre- and post-treatment mean index lesion and PVNT absorbed doses, and V200, D70, D50 were strongly correlated (Pearsons Correlation Coefficient > 0.65, p < 0.05).

conclusion

Indexed as

Hepatocellular CarcinomaPET/CTRadioembolizationSPECT/CTTechnetium-99m macroaggregated albuminYttrium-90

Identifiers

PMID42576071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.