Evidence map›Paper›PMID 42576014›Full record

ReviewNature cell biology2026

Advanced imaging of membrane contact sites.

Riccardo Filadi, Ambra Bertocco, Michela Rossini, Paola Pizzo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riccardo FiladiDepartment of Biomedical Sciences, University of Padua, Padua, Italy. riccardo.filadi@cnr.it.ORCID http://orcid.org/0000-0002-5871-2620
Ambra Bertocco *Department of Biomedical Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0002-8018-6989
Michela Rossini *Department of Biomedical Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0009-0008-9482-0371
Paola PizzoDepartment of Biomedical Sciences, University of Padua, Padua, Italy. paola.pizzo@unipd.it.ORCID http://orcid.org/0000-0001-6077-3265

Funding

Alzheimer's Association E2A-23-1148250Ministero dell'Istruzione, dell'Università e della Ricerca (Ministry of Education, University and Research) PRIN P20225R4Y5
6 · The paper itself

Abstract

Organelle membrane contact sites (MCSs) coordinate key cell activities and their alterations are associated with several high-incidence disorders, prompting an increasing interest in their study. However, the investigation of MCSs is challenging, mostly because of their nanometric size and dynamic nature. Here we highlight the methods that are available for analysing MCSs. We focus on advanced imaging techniques and discuss their advantages and limitations, providing practical guidance for researchers approaching this field. We propose to study MCSs through a combination of different methodologies, complementing their visualization with investigation of the associated functions. To this end, we also discuss the need to develop innovative biosensors.

Indexed as

Intracellular MembranesMolecular ImagingAnimalsBiosensing TechniquesCell MembraneHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.