Evidence map›Paper›PMID 42574871›Full record

ArticleSocial science & medicine (1982)2026

"I don't know how to treat you": Testosterone and gynecological care for transmasculine and gender diverse adults.

Diana M Tordoff, Alic Shook, G Oscar Anderson, Meg Quint, Annesa Flentje, Mitchell R Lunn, Juno Obedin-Maliver

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diana M TordoffDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, CA, USA; The PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA. Electronic address: dtordoff@stanford.edu.
Alic ShookCollege of Nursing & Health Sciences, Seattle University, Seattle, WA, USA.
G Oscar AndersonThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA; Community Healthcare Network, New York, NY, USA.
Meg QuintThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA; Stanford University School of Medicine, Palo Alto, CA, USA.
Annesa FlentjeThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.
Mitchell R LunnThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA; Department of Epidemiology and Population Health, Stanford University School of Medicine, Palo Alto, CA, USA.
Juno Obedin-MaliverDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, CA, USA; The PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, CA, USA; Department of Epidemiology and Population Health, Stanford University School of Medicine, Palo Alto, CA, USA.

Funding

Mentoring the next generation of substance use, HIV, and epigenetic researchers in sexual and gender minority healthK24DA057874 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Annesa Flentje · 2023 to 2026
$793k
The Impact of Testosterone on Vaginal Atrophy and the Vaginal Microbiome in Transgender MenK01AI182507 · NIAID · STANFORD UNIVERSITY · PI Diana Marie Tordoff · 2024 to 2026
$394k
NIAID NIH HHS K01 AI182507NIDA NIH HHS K24 DA057874
6 · The paper itself

Abstract

Many transmasculine and gender diverse people assigned female at birth people use testosterone as gender-affirming hormone therapy, which is associated with significant changes to sexual and reproductive health. Additionally, transmasculine people experience significant barriers to accessing gynecological care. This study examined the perceived role of testosterone in individuals' gynecological health and how testosterone use shaped access to gynecological care for transmasculine people. We conducted in-depth qualitative interviews with 28 transmasculine and gender diverse adults currently using testosterone in the United States. Participants were recruited through PRIDEnet, a national community engagement network of LGBTQIA+ individuals and organizations. Data were analyzed using thematic analysis. Participants described a range of gynecological concerns, most commonly pelvic pain, genital atrophy, and recurrent urogenital infections. Six interrelated themes emerged: erasure, authority of knowledge, navigating uncertainty regarding testosterone's gynecological effects, prolonged and fragmented care pathways, cumulative exposure, and resistance and agency. Informational, institutional, and identity erasure frequently limited provider knowledge and constrained clinical decision-making, while conflicts over the authority of knowledge privileged diagnostic certainty over embodied experience. These dynamics contributed to prolonged healthcare journeys characterized by repeated referrals, excessive testing, unresolved symptoms, and diagnostic uncertainty. Repeated exposure to dismissive and delayed care, and care that was not trauma-informed accumulated, becoming embodied as medical trauma, overwhelm, disengagement from care, and diminished well-being. Despite these challenges, participants engaged in resistance and agency through self-advocacy and community knowledge. Improving gynecological care for transmasculine people requires expanded research on the gynecological effects of testosterone, improved provider education, and trauma-informed, trans-competent care models that value embodied patient knowledge.

Indexed as

GynecologyTestosteroneTransgender PersonsAdultFemaleGender-Nonconforming PersonsHealth Services AccessibilityHumansInterviews as TopicMaleMiddle AgedQualitative ResearchUnited StatesTestosteroneEcosocial theoryErasureGynecological healthTestosteroneTransgender

Identifiers

PMID42574871
PMCPMC13632817

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.