Evidence map›Paper›PMID 42574867›Full record

ArticleSocial science & medicine (1982)2026

Lasting effects of redlining: The association of historical redlining and cognitive function in older Black adults.

Brittney S Lange-Maia, Melissa Lamar, Jason LaBrosse, Ana W Capuano, V Eloesa McSorley, Francine Grodstein, Bryan D James, Lisa L Barnes

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Brittney S Lange-MaiaRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Family and Preventive Medicine, Rush University Medical Center, United States. Electronic address: Brittney_Lange-Maia@Rush.edu.
Melissa LamarRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, United States.
Jason LaBrosseRush Alzheimer's Disease Center, Rush University Medical Center, United States.
Ana W CapuanoDepartment of Neurology and Public Health Sciences, University of Chicago, United States.
V Eloesa McSorleyRush Alzheimer's Disease Center, Rush University Medical Center, United States.
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Internal Medicine, Rush University Medical Center, United States.
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Internal Medicine, Rush University Medical Center, United States.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, United States; Department of Neurological Sciences, Rush University Medical Center, United States.

Funding

Rush Alzheimer's Disease Research CenterP30AG072975 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Lisa L Barnes, Julie A. Schneider · 2021 to 2026
$24.7M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
Multilevel Contributors to Cognitive and Physical Function Decline in Older African AmericansR03AG071943 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LANGE MAIA, BRITTNEY SUSANNE · 2021 to 2021
$308k
NIA NIH HHS P30 AG072975NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG062711NIA NIH HHS R03 AG071943
6 · The paper itself

Abstract

backgroundResiding in a formerly redlined community is often associated with worse health. Few studies have studied redlining and late-life cognition; none have examined multiple cognitive domains.

methodsBlack older adults (N = 676, mean baseline age 74.1 [SD: 6.5] years, 78.2% female) from two cohorts in Chicago, IL completed annual cognitive assessments of episodic, semantic, and working memory, perceptual speed, and visuospatial ability. Baseline geocoded addresses were matched to historic Home Owners' Loan Corporation grades ("best," "still desirable," "definitely declining," and "redlined" [first two combined in analyses]). Grades served as place-based proxies for the culmination of decades of policies that heavily impacted redlined communities. Linear mixed-effects models tested associations between grade and change in global and domain-specific cognition, adjusting for age, sex, and years of education.

resultsCompared to those in communities graded as "best/still desirable," participants in redlined communities had lower initial global cognition (β = 0.14, SE = 0.05, p = 0.01), though there were no differences for those in "definitely declining" communities, or differences in the rate of longitudinal change. For cognitive domains, those in redlined communities had lower initial episodic and working memory (β = -0.13, SE = 0.07, p = 0.04 and β = -0.17, SE = 0.08, p = 0.03, respectively), but slower decline in semantic memory (β = 0.03, SE = 0.01, p = 0.04) compared to those in "best/still desirable" communities. Results remained consistent when considering potential mediators related to health status, present-day community resources characteristics, and spatial correlations.

conclusionsResiding in a historically redlined community is associated with cognition in older Black adults, indicating importance of historical community context, though these results are nuanced.

Indexed as

Black or African AmericanCognitionAgedAged, 80 and overChicagoFemaleHumansMaleResidential Segregation

Identifiers

PMID42574867
PMCPMC13623191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.