Evidence map›Paper›PMID 42574653›Full record

ArticleMolecular carcinogenesis2026

Chemopreventive Effect of Bitter Melon (Momordica charantia) Juice on Pancreatic Carcinogenesis in LSL-Kras

Lakshmi Sai Pratyusha Bugata, Deepanshi Dhar, Rama Kant, Robin Kumar, Md Imtiazul Kabir, Chapla Agarwal, Rajesh Agarwal, Komal Raina

Abstract read
In one paragraph

Article in Molecular carcinogenesis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lakshmi Sai Pratyusha BugataDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.
Deepanshi DharDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Rama KantDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0002-0550-1467
Robin KumarDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.
Md Imtiazul KabirDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.
Chapla AgarwalDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0003-1146-4890
Rajesh AgarwalDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0002-9455-0235
Komal RainaDepartment of Pharmaceutical Sciences, South Dakota State University, Brookings, South Dakota, USA.ORCID https://orcid.org/0000-0003-0371-1070

Funding

Molecular mechanism of bitter melon juice efficacy against pancreatic cancer.R01CA195708 · NCI · UNIVERSITY OF COLORADO DENVER · PI AGARWAL, RAJESH · 2014 to 2018
$2.2M
NCI NIH HHS R01 CA195708NIH HHS R01CA195708
6 · The paper itself

Abstract

Herein, using the LSL-Kras

Indexed as

CarcinogenesisCarcinoma, Pancreatic DuctalMomordica charantiaPancreatic NeoplasmsPlant ExtractsProto-Oncogene Proteins p21(ras)AnimalsDisease Models, AnimalFemaleHumansMiceMice, TransgenicPancreasHras protein, mousePlant ExtractsProto-Oncogene Proteins p21(ras)bitter meloncancer preventionKrasG12D/+ modelMomordica charantiapancreatic cancerpancreatic ductal adenocarcinoma

Identifiers

PMID42574653
PMCPMC13656185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.