ArticleProceedings of the National Academy of Sciences of the United States of America2026
Molecular assembly as a universal biosignature measurable by mass spectrometry.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Molecular assembly as a universal biosignature measurable by mass spectrometry.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Detecting life beyond Earth requires biosignatures that do not depend on the chemistry of known organisms. Molecular assembly (MA), derived from Assembly Theory, quantifies how difficult it is to build a molecule from basic building blocks, linking complexity directly to selection and evolution. Here, we show that MA can serve as a universal biosignature that is both interpretable and experimentally measurable. Unlike information-theoretic measures, MA can be inferred directly from mass spectrometry data without structural elucidation. We demonstrate this using a machine learning model trained on standardized single-stage (MS
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Registered trials
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