Evidence map›Paper›PMID 42574604›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

High-yield charge separation along the alternative path in a photosynthetic reaction center: X-ray structure and electrostatic analysis.

Stephen M Keable, Rongmei Judy Wei, James C Buhrmaster, Stephen Hippleheuser, Hiroki Makita, Philipp S Simon, Gregory A Tira, Moritz Kretzschmar, Isabel Bogacz, Kaitlyn M Faries and 19 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Stephen M KeableMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0003-0072-2604
Rongmei Judy WeiPh.D. Program in Chemistry, The Graduate Center, City University of New York, New York, NY 10016.
James C BuhrmasterBiosciences Division, Argonne National Laboratory, Lemont, IL 60439.
Stephen HippleheuserBiosciences Division, Argonne National Laboratory, Lemont, IL 60439.ORCID 0009-0002-2657-2456
Hiroki MakitaMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Philipp S SimonMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-2859-4475
Gregory A TiraBiosciences Division, Argonne National Laboratory, Lemont, IL 60439.
Moritz KretzschmarMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Isabel BogaczMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Kaitlyn M FariesDepartment of Chemistry, Washington University, St. Louis, MO 63130.
Anthony LanMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Isabela I NangcaMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0003-4159-1970
Miao ZhangMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Margaret D DoyleMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-7289-3544
Petko ChernevMolecular Biomimetics, Department of Chemistry-Ångström, Uppsala University, Uppsala, Sweden.
Asmit BhowmickMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Daniel W PaleyMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.
Nicholas K SauterMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0003-2786-6552
Aaron S BrewsterMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-0908-7822
Kensuke TonoRIKEN SPring-8 Center, Sayo-cho, Sayo-gun, Hyogo 679-5148, Japan.ORCID 0000-0003-1218-3759
Shigeki OwadaRIKEN SPring-8 Center, Sayo-cho, Sayo-gun, Hyogo 679-5148, Japan.ORCID 0000-0002-1451-7612
Junko YanoMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0001-6308-9071
Vittal K YachandraMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-3983-7858
M R GunnerPh.D. Program in Chemistry, The Graduate Center, City University of New York, New York, NY 10016.ORCID 0000-0003-1120-5776
Christine KirmaierDepartment of Chemistry, Washington University, St. Louis, MO 63130.ORCID 0000-0003-1825-4546
Dewey HoltenDepartment of Chemistry, Washington University, St. Louis, MO 63130.ORCID 0000-0003-3639-6345
Deborah K HansonBiosciences Division, Argonne National Laboratory, Lemont, IL 60439.ORCID 0000-0002-2208-583X
Philip D LaibleBiosciences Division, Argonne National Laboratory, Lemont, IL 60439.ORCID 0000-0003-2600-7991
Jan F KernMolecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.ORCID 0000-0002-7272-1603

Funding

Biological Spectroscopy and Crystallography Using an X-ray Free Electron Laser - Supplemental EquipmentR01GM110501 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Junko Yano · 2014 to 2026
$4.8M
High throughput sample delivery method for time resolved studies of enzyme reactions with X-ray and complementary techniquesR01GM126289 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI KERN, JAN F · 2017 to 2025
$4.6M
DIALS: supporting structural biology through open source diffraction processing softwareR24GM154040 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Aaron Samuel Brewster · 2024 to 2026
$3.7M
Taking Snapshots of Enzymatic Reactions Using X-ray Crystallography and SpectroscopyR35GM149528 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI VITTAL YACHANDRA · 2023 to 2026
$2.7M
Cctbx.xfel: Serial crystallography computational methods aimed at biomolecular functionR35GM151988 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI NICHOLAS K SAUTER · 2024 to 2026
$2.2M
DOE | SC | Basic Energy Sciences (BES) DE-AC02-05CH11231DOE | SC | Basic Energy Sciences (BES) DE-AC02-06CH11357DOE | SC | Basic Energy Sciences (BES) DE-CD0002036DOE | SC | Basic Energy Sciences (BES) DE-SC0001423HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM110501HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM126289HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM149528HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM151988HHS | NIH | National Institute of General Medical Sciences (NIGMS) R24GM154040NIGMS NIH HHS R01 GM110501NIGMS NIH HHS R01 GM126289NIGMS NIH HHS R24 GM154040NIGMS NIH HHS R35 GM149528NIGMS NIH HHS R35 GM151988
6 · The paper itself

Abstract

In all photosynthetic reaction centers (RC), transmembrane electron-transfer (ET) cofactor pathways are coordinated by homologous peptides and arranged with approximate C

Indexed as

Photosynthetic Reaction Center Complex ProteinsAmino Acid SubstitutionBacterial ProteinsCrystallography, X-RayElectron TransportModels, MolecularPhotosynthesisProtein ConformationRhodobacter sphaeroidesStatic ElectricityBacterial ProteinsPhotosynthetic Reaction Center Complex Proteinselectron transferphotosynthesispurple bacterial reaction center

Identifiers

PMID42574604
PMCPMC13486545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.