Evidence map›Paper›PMID 42574063›Full record

ArticleArthritis & rheumatology (Hoboken, N.J.)2026

Type I Interferon Drives Dysfunction of a Distinct CD8

Huizhong Long, Elio Carmona, Mikhail G Dozmorov, Amr H Sawalha

Abstract read
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In one paragraph

Article in Arthritis & rheumatology (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Huizhong LongDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Elio CarmonaDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Mikhail G DozmorovDepartment of Biostatistics, Virginia Commonwealth University, Richmond.
Amr H SawalhaDivision of Rheumatology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID https://orcid.org/0000-0002-3884-962X

Funding

National Institute of Allergy and Infectious Diseases R01 AI097134
6 · The paper itself

Abstract

objectiveSystemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA-DRB1 and STAT1 in SLE CD8

methodsPeripheral blood CD8

resultsCD8

conclusionCD8

Identifiers

PMID42574063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.