Evidence map›Paper›PMID 42573948›Full record

ArticleCJEM2026

Treatment interventions and outcomes of stroke patients transported by helicopter emergency medical services to a comprehensive stroke center.

M Freymond, K Genise, D O'Dochartaigh, E Violato, J Holodinsky, J P Berard, K Lin

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Article in CJEM, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M FreymondDepartment of Emergency Medicine, University of Calgary, Calgary, AB, Canada.ORCID http://orcid.org/0009-0001-1913-3976
K GeniseDepartment of Emergency Medicine, University of Calgary, Calgary, AB, Canada.
D O'DochartaighShock Trauma Air Rescue Service, Edmonton, AB, Canada.
E ViolatoCentre for Advanced Medical Simulation, Northern Alberta Institute of Technology, Edmonton, AB, Canada.
J HolodinskyDepartment of Emergency Medicine, University of Calgary, Calgary, AB, Canada.
J P BerardShock Trauma Air Rescue Service, Winnipeg, MB, Canada.
K LinDepartment of Emergency Medicine, University of Calgary, Calgary, AB, Canada. katie.lin@albertahealthservices.ca.ORCID http://orcid.org/0000-0003-2000-2073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHelicopter Emergency Medical Services (EMS) can expedite transport for patients with acute ischemic stroke, yet many cases do not ultimately receive neuro-intervention (i.e., endovascular thrombectomy or neurosurgical procedure). Expanded stroke treatment time windows have increased the number of potential thrombectomy-eligible patients, adding urgency to appropriate resource utilization. The purpose of this study was to describe characteristics and clinical outcomes of patients with known or suspected ischemic stroke transported via helicopter EMS and identify pre-transport factors associated with receiving neuro-intervention.

methodsThis four-year population study evaluated adults with confirmed or suspected ischemic stroke transported via helicopter EMS to a comprehensive stroke center in Alberta (Jan 1, 2019 to Dec 31, 2022). The primary outcome was the proportion of patients who received neuro-intervention. Secondary outcomes included neuro-intervention rates comparing early (i.e., < 6 h from 'last seen normal') and late (≥ 6 h) presenters, proportion of 'low-yield' transfers (i.e., died/palliated or discharged/repatriated within 24 h without neuro-intervention), and a comparison of pre- and intra-transport characteristics of patients who received neuro-intervention to those who did not. Exploratory multivariable regression was used to identify pre-transport predictors of neuro-intervention.

resultsOf 226 patients included in this study, 35% (n = 80) received neuro-intervention, with no difference between early (n = 55/154) and late (n = 20/64) presenters (p = 0.64). Conversely, 23% (n = 52) of cases constituted potential 'low-yield' transports. Neuro-intervention rates increased with pre-transport imaging (54% vs. 26%, p < 0.001), pre-transport thrombolysis (33 vs. 13%, p < 0.001) and Los Angeles Motor Scale (LAMS) of 4-5 (92 vs. 63%, p = 0.006). Pre-transport imaging (OR 5.3; 95% CI 1.8-10.7) and thrombolysis (OR 2.8; 95% CI 1.1-12.9) were associated with neuro-intervention.

conclusionApproximately one-third of helicopter EMS transports for confirmed or suspected ischemic stroke resulted in neuro-intervention. Pre-transport imaging and thrombolysis were strongly associated with neuro-intervention, underscoring the important role of primary stroke centers in optimizing patient care and resource utilization.

Indexed as

Acute ischemic strokeHelicopter EMSHEMSPre-hospitalStrokeTransport

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.