Evidence map›Paper›PMID 42573791›Full record

ArticleArchives of microbiology2026

Streptomyces griseoincarnatus AR2 from the cold desert as a biofactory for secondary metabolites with multifaceted bioactivities, confirmed by in vitro and in silico approaches.

Arisha Rameen Bhatti, Noor Hassan, Hazrat Ali, Noor Ul Huda, Abdul Tawab, Saba Khan, Ambreen Latif, Asad Ali, Waseem Abbas, Iqra Latif Ghuman and 4 more

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Article in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Arisha Rameen BhattiFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Noor HassanFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan. noorhassan672@gmail.com.ORCID https://orcid.org/0000-0002-6619-6806
Hazrat AliFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Noor Ul HudaFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Abdul TawabHealth Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Saba KhanHealth Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Ambreen LatifFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Asad AliFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Waseem AbbasHealth Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Iqra Latif GhumanFermentation Biotechnology for Industrial Products (FBIP) Group, Industrial Biotechnology Division, National Institute for Biotechnology and Genetic Engineering-College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad, Pakistan.
Mohsin KhanDepartment of Biological Sciences, Ohio University, Athens, USA.
Aiman UmarLAPTIAB, National Research and Innovation Agency (BRIN), South Tangerang, Indonesia.
Zara RafaqueDepartment of Microbiology, Hazara University, Mansehra, Pakistan.
Muhammad RafiqDepartment of Microbiology, Faculty of Life Sciences and Informatics, Balochistan University of IT, Engineering and Management Sciences, Quetta, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exploring natural pigments and multifunctional metabolites from the genus Streptomyces is experiencing global escalation, especially for health-related applications. The current study reports bioactive potential of deep yellow pigment and other metabolites from Streptomyces griseoincarnatus AR2, previously recovered from Katpana Cold Desert, Gilgit-Baltistan, Pakistan. Peptone glycerol (PG) medium supported extracellular pigment release and yielded a crude pigment at 20.64 g/L. The pigment was purified through chromatography, demonstrated R

Indexed as

Pigments, BiologicalStreptomycesAnti-Bacterial AgentsAntifungal AgentsAntioxidantsAspergillus nigerBacillus subtilisDesert ClimateHumansMicrobial Sensitivity TestsMolecular Docking SimulationSecondary MetabolismAnti-Bacterial AgentsAntifungal AgentsAntioxidantsPigments, BiologicalAlloxanthinEpithenamycin BResistomycinSecondary metabolitesStreptomyces griseoincarnatus

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.