Evidence map›Paper›PMID 42573628›Full record

ArticlePediatric surgery international2026

Outcomes of laparoscopic versus open excision of choledochal cyst in preschool-aged children: analysis from a nationally representative database.

Maria Grazia Sacco Casamassima, Nadeen Alturki, Janelle R Noel-MacDonnell, Tolulope A Oyetunji, Shawn D St Peter

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Maria Grazia Sacco CasamassimaDepartment of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas, MO, 64108, USA. msaccocasamassim@cmh.edu.
Nadeen AlturkiDepartment of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas, MO, 64108, USA.
Janelle R Noel-MacDonnellDepartment of Health Services and Outcomes Research, Children's Mercy Hospital, 2401 Gillham Road, Kansas, MO, 64108, USA.
Tolulope A OyetunjiDepartment of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas, MO, 64108, USA.
Shawn D St PeterDepartment of Surgery, Children's Mercy Kansas City, 2401 Gillham Road, Kansas, MO, 64108, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic surgery for choledochal cysts (CC) in young children is a technically demanding procedure, and comparative outcomes with open surgery remain incompletely defined. This study aims to compare outcomes of laparoscopic surgery (LS) and open surgery (OS) in children ≤ 5 years.

methodsA retrospective cohort study was conducted using the Pediatric Health Information System (PHIS) database to identify children with CC who underwent definitive surgical excision between 2015 and 2025. Patients were grouped by operative approach (LS vs. OS). Demographic characteristics, operative techniques, and postoperative outcomes were compared.

resultsA total of 533 children were included (LS: 251, 47.1%; OS: 282, 52.9%). LS was more often performed during elective admissions (p < 0.001) and in older children (p < 0.001). Preoperative malnutrition (p = 0.032), cholangitis (p = 0.029), and the need for drainage procedures prior to definitive surgery (p = 0.050) were more common in OS. Hepaticoduodenostomy predominated in LS, while hepaticojejunostomy was more common with OS (p < 0.001). There were no differences in overall 90-day postoperative complications (p = 0.618). LS was associated with fewer blood transfusions (p = 0.049), total parenteral nutrition (p = 0.005), and mechanical ventilation (p = 0.001), decreased odds of intensive care unit admission (p < 0.001), and shorter length of stay (p < 0.001). At 90-day follow-up, biliary calculi were more common after LS (2.8% vs. 0.4%, p = 0.029), while hepatic fibrosis was observed only after OS (3.5%, p = 0.002).

conclusionIn preschool-aged children with choledochal cysts, laparoscopic and open approaches demonstrate similar short-term complication rates. Laparoscopy is associated with improved perioperative recovery and reduced resource utilization. When patient and disease factors permit, LS represents a reasonable primary operative approach, although careful patient selection remains essential.

Indexed as

Choledochal CystLaparoscopyChild, PreschoolDatabases, FactualFemaleHumansInfantMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeChildrenCholedochal cystLaparoscopic surgeryOpen surgeryPediatric hepatobiliary surgeryPHIS

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.