ReviewACS biomaterials science & engineering2026
Valorization of Silkworm Cocoons into Sustainable Nanomaterials: Applications and Challenges.
Review in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silk fibroin (SFb) derived from silkworm cocoons (Bombyx mori) is increasingly recognized as an innovative biodegradable protein for sustainable applications. We discuss its wide biomedical and industrial applications based on the review of 1791 articles from 2001 to 2025 (Scopus). There has been a large increase in research, with 66.44% of publications and 74.84% of citations during 2019-2025. SFb-based nanomaterials have excellent performance in tissue engineering (18.53%), drug delivery (60.59%), and in novel areas, including flexible electronics and sustainable construction, owing to their high strength, controllable structure, and optical transparency. Crucially, exploiting ∼50,000 tonnes of annual silk industry cocoon valorization for aerogels, hydrogels, and NPs promotes the circular economy and minimizes environmental impact using green technologies (lower kg CO2/kg fibroin). These developments make a direct, but by no means exclusive, contribution to the UN Sustainable Development Goals, in particular health (SDG 3), innovation (SDG 9), sustainable production (SDG 12), and climate action (SDG 13). Still, scaling, costs, and the long-term environmental consequences are hurdles. However, such concerns will need to be addressed through sustainable biomanufacturing and life-cycle assessments if SFb can be used to its full potential for a greener future.
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Registered trials
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