Evidence map›Paper›PMID 42573259›Full record

ArticleApplied and environmental microbiology2026

Utilizing natural competence to genetically manipulate

Kevin Y Cao, Daniella Serrador, Jhenielle R Campbell, Rupert Kaul, William Wiley Navarre

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kevin Y CaoDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Daniella SerradorDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Jhenielle R CampbellDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Rupert KaulDepartments of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1586-4093
William Wiley NavarreDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-9293-9220

Funding

CIHR CGS-DCIHR PJT-198144IGNITE grant from the Emerging Pandemics and Infections Consortium (EPIC) IGNITENatural Sciences and Engineering Research Council of Canada RGPIN-2020-06015
6 · The paper itself

Abstract

The healthy human vaginal microbiota is typically dominated by one species of IMPORTANCE: This study describes, to our knowledge, the first method for genetically manipulating

Indexed as

LactobacillusBacterial ProteinsFemaleHumansTransformation, BacterialVaginaBacterial Proteinscompetence proteinserythromycin resistancegene editinggenome editinginerolysinlactobacillilactobacillus inersnatural transformationvaginal microbiome

Identifiers

PMID42573259
PMCPMC13599483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.