ArticleInfection and drug resistance2026
Antimicrobial Resistance, Molecular Epidemiology, and Virulence Profiles of Hypervirulent Carbapenem-Resistant
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To systematically analyze the drug resistance phenotype, virulence characteristics, and molecular epidemiological characteristics of hypervirulent carbapenem-resistant Methods: A total of 91 hv-CRKP strains were collected from the First People's Hospital of Zunyi from 2021 to 2023. Drug susceptibility test was performed for commonly used antibiotics in clinic. Molecular typing included PCR detection of carbapenemase gene, multilocus sequence typing (MLST), membrane porin (OmpK) deletion analysis, and capsule serotyping. The virulence phenotype of hv-CRKP was comprehensively evaluated by biofilm formation, serum resistance, and Results: hv-CRKP strains were highly resistant to commonly used antibiotics, but the resistance rate to tigecycline was relatively low, only 3.3%. The clones carrying virulence genes Conclusion: The main hv-CRKP strains in this region carry the
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