ArticleRomanian journal of ophthalmology
Gouty tophus on the eyelid.
Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A gouty tophus on the eyelid is a casuistic flash in the routine biopsy flow. There has been a 12th case reported in the literature, along with an analysis of the distribution by age, sex, location, size, and symptoms. Male gender predominates (10:2) within a wide age range (26-79 years), after a several-year history of gout, affecting mainly the canthi and, in only 4 cases, the middle area of the eyelids (the upper eyelid more often), with dimensions ranging from 4 to 14 mm. The tophi can be multiple (in 2 cases). In addition to aesthetic concerns and discomfort, the tophi caused mechanical ptosis of the eyelid on two occasions. A histologically confirmed eyelid tophus may serve as an early diagnostic stigma of the disease, even in the absence of hyperuricemia. Their occurrence may be either a manifestation of disseminated skin tophi or a localized disturbance of the protective alkaline homeostasis of the eyelid tissue.
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