Evidence map›Paper›PMID 42572668›Full record

ArticleCureus2026

When Steroids Backfire: A Case of Hyperosmolar Hyperglycemic State, Pneumocystis Pneumonia, and Cauda Equina Syndrome.

Bryson T Grondel, Neel Patel, Chris Talone, Nathalie Vanderrijst

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bryson T GrondelGraduate Medical Education, Inspira Medical Center, Mullica Hill, USA.
Neel PatelInternal Medicine, Inspira Medical Center, Mullica Hill, USA.
Chris TaloneRadiology, University at Albany, State University of New York, Albany, USA.
Nathalie VanderrijstCritical Care Medicine, Cooper University Hospital, Camden, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corticosteroids are potent anti-inflammatory and immunosuppressive agents frequently used in short courses for various conditions. However, prolonged or inappropriate use can lead to severe complications, including immunosuppression, metabolic derangements, and delayed diagnosis of underlying disease. Cauda equina syndrome is a neurosurgical emergency that can be masked by corticosteroid therapy, while chronic use also predisposes to opportunistic infections such as

Indexed as

cauda equine syndromehyperosmolar hyperglycemic state (hhs)pjp pneumoniaprednisone treatmentsteroid overuse

Identifiers

PMID42572668
PMCPMC13453325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.