ReviewCureus2026
Impact of Running on the Risk and Progression of Knee Osteoarthritis: A Review of Current Evidence.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review evaluates the safety of recreational running for knee health, defining the "biomechanical window" based on the latest evidence (2020-2024). The available evidence reveals a U-shaped risk curve, indicating that moderate recreational running is highly protective against knee osteoarthritis (KOA) compared with both sedentary lifestyles and elite, high-volume running. In patients over 50 years of age with existing OA, running does not accelerate structural damage and effectively reduces pain when managed through gradual load progression (the "10% rule"). Recreational running is a safe, chondroprotective intervention. Clinical guidelines should favour individualized load titration over the unfounded discouragement of activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.