ArticleAnnals of medicine2026
Incidence and factors influencing the occurrence of postoperative thrombosis in patients with lower limb fractures across different age groups: a retrospective study.
Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPostoperative venous thrombosis (PVT) is a common complication following lower limb fracture surgery, yet age-specific risk factors remain unclear. This study aimed to identify distinct predictors and develop tailored prediction models for young/middle-aged and elderly patients. PATIENTS AND
methodsThis multicentre retrospective cohort study analysed factors influencing of PVT in 483 patients undergoing lower limb fracture surgery at two tertiary hospitals between 1 January 2020 and 31 December 2022. Participants were divided into young/middle-aged (18-59 years,
resultsThe overall PVT incidence was 15.24% and 23.36% (
conclusionsFracture patients of different age groups require distinct risk management and perioperative treatments. This study developed age-specific PVT prediction models, highlighting the different risk profiles between young/middle-aged and elderly patients. For young/middle-aged patients, preoperative coagulation status should be optimized, postoperative anticoagulant overuse limited and fluid volume recovery enhanced. For elderly patients, intraoperative fluid input should be strictly restricted, and postoperative protein and electrolyte levels monitored.
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