ArticleNeurologia medico-chirurgica2026
Correlation of Preoperative Diffusion-weighted Magnetic Resonance Imaging-based Virtual Elastography with Intraoperative Quantitative Tumor Stiffness in Meningiomas.
Article in Neurologia medico-chirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Tumor stiffness strongly influences exposure, extent of resection, operative time, and approach in meningioma surgery, but magnetic resonance imaging-based prediction still relies mainly on qualitative assessment. We evaluated whether a diffusion-derived stiffness surrogate calculated from diffusion-weighted magnetic resonance imaging-based virtual elastography correlates with intraoperative quantitative tumor stiffness in meningiomas and assessed its usefulness for preoperative stiffness prediction. Of 33 patients who underwent meningioma surgery between May 2022 and January 2025, 22 with both preoperative virtual elastography and intraoperative stiffness measurements were analyzed. Preoperative 3-Tesla diffusion-weighted magnetic resonance imaging with 2 b values was used to generate shifted apparent diffusion coefficient maps, and a single-slice volume of interest with a 5.51 mm slice thickness was manually delineated on the axial slice showing the largest tumor cross-sectional area. Intraoperative tumor stiffness of approximately 1-cm
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