Evidence map›Paper›PMID 42572007›Full record

Observational studyJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026

High-Frequency Ultrasound Assessment of Female Genital Rejuvenation.

Luciana Zattar, Natália Venturelli Marques de Souza

Abstract readObservational Study
In one paragraph

Observational study in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luciana ZattarHospital Sírio-Libanês, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-5229-8596
Natália Venturelli Marques de SouzaClínica Venturelli, São Paulo, Brazil.ORCID https://orcid.org/0009-0005-5477-1964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the role of high-frequency ultrasound (HFUS) in the anatomical evaluation and monitoring of female genital rejuvenation procedures and to illustrate characteristic sonographic patterns associated with commonly used aesthetic treatments.

methodsThis retrospective observational study reviewed anonymized clinical and ultrasound records from eight female patients who underwent genital rejuvenation in a private dermatologic ultrasound center. HFUS examinations were performed using 20-33 MHz linear probes in standardized B-mode, with color Doppler added when indicated. Representative cases were selected to demonstrate normal anatomy, age-related changes, postprocedural findings, and complications.

resultsHFUS provided high-resolution visualization of the epidermis, dermis, subcutaneous tissue, and fascial planes of the external genitalia. Younger patients showed compact fat lobules and well-defined fascial layers, whereas older patients exhibited dermal thinning and a subepidermal low-echogenicity band. Postprocedural HFUS identified distinct patterns for each treatment modality, including anechoic lobulated deposits after hyaluronic acid, hyperechoic punctate "snowfall" reflections after calcium hydroxyapatite, linear hyperechoic structures after absorbable threads, and focal hyperechoic panniculitis following lipolytic mesotherapy. HFUS also aided in detecting and characterizing treatment-related changes and potential complications.

conclusionsHFUS appears to be a useful adjunct for minimally invasive female genital rejuvenation, enabling detailed anatomical assessment, visualization of injected materials, and monitoring of treatment-related changes. These preliminary findings support the integration of HFUS into aesthetic practice and highlight the need for further studies to standardize its application in this growing field.

Indexed as

Cosmetic TechniquesGenitalia, FemaleRejuvenationAdultAgedFemaleHumansMiddle AgedRetrospective StudiesUltrasonographyabsorbable threadsaesthetic gynecologycalcium hydroxyapatitefemale genital rejuvenationhigh‐frequency ultrasoundhyaluronic acid

Identifiers

PMID42572007
PMCPMC13578586

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.