Evidence map›Paper›PMID 42572005›Full record

ArticleJournal of extracellular vesicles2026

Lymphatic Drainage of Cerebrospinal Fluid Using Lymph Node Seeker 64Cu-Labeled Gram-Negative Bacterial Extracellular Vesicles With Positron Emission Tomography (PET).

Kyuwan Kim, Changjin Lee, Hayoung Shin, Ran Ji Yoo, Yoori Choi, Chanwoo Lee, Insoo Kim, Jaewook Lee, Minseok Suh, Yun-Sang Lee and 2 more

Abstract read
In one paragraph

Article in Journal of extracellular vesicles, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kyuwan KimDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.ORCID https://orcid.org/0000-0002-9462-9971
Changjin LeeSL Bigen Co. Ltd., Incheon, South Korea.
Hayoung ShinDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.
Ran Ji YooDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
Yoori ChoiDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
Chanwoo LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.
Insoo KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.
Jaewook LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.
Minseok SuhDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
Yun-Sang LeeDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.
Yong Song GhoDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea.ORCID https://orcid.org/0000-0003-3366-2345
Dong Soo LeeDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, South Korea.ORCID https://orcid.org/0000-0001-9013-4835

Funding

National Research Foundation of Korea
6 · The paper itself

Abstract

Cerebrospinal fluid (CSF) is drained into the systemic lymphatics via paravertebral lymph nodes. Superficial and deep cervical lymph nodes collect CSF in mice, but the exact and quantified routes are unknown. Recently, we simultaneously visualized cervical, sacral and iliac lymph nodes via serial imaging on the intrathecal [

Indexed as

Cerebrospinal FluidCopper RadioisotopesEscherichia coliExtracellular VesiclesGram-Negative BacteriaLymph NodesPositron-Emission TomographyAnimalsBrainFemaleMiceSpinal CordCopper-64Copper Radioisotopes[64Cu]Cu‐extracellular vesicle PETcerebrospinal fluid‐lymphatic drainageextracellular vesiclesouter membrane vesiclesparavertebral lymph nodes

Identifiers

PMID42572005
PMCPMC13453943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.