Evidence map›Paper›PMID 42571699›Full record

ArticleChemistry & biodiversity2026

Ethnopharmacological and Antiaging Evaluation of Salvia cadmica: Modulation of MMP1/MMP3 and Collagen in Oxidative Stress-Induced Senescence.

Nilay Isitez, Erman Salih Istifli, Cengiz Sarikurkcu, Sevim Feyza Erdogmus

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nilay IsitezFaculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-1928-7158
Erman Salih IstifliFaculty of Arts and Sciences, Cukurova University, Adana, Turkey.ORCID https://orcid.org/0000-0003-2189-0703
Cengiz SarikurkcuFaculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0001-5094-2520
Sevim Feyza ErdogmusFaculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-4319-7558

Funding

Scientific Research Projects Coordination Unit of Afyonkarahisar Health Sciences University 24.TEMATİK.003
6 · The paper itself

Abstract

Salvia cadmica, an Anatolian endemic species traditionally used for wound healing and inflammation, has been scarcely investigated for its anti-aging potential. In this study, the aqueous-ethanol extract of S. cadmica was evaluated for its antioxidant, cytoprotective, and anti-senescence effects using in vitro and in silico approaches. LC-ESI-MS/MS analysis identified rosmarinic acid (3447 µg/g), luteolin 7-glucoside (767 µg/g), and luteolin (586 µg/g) as major constituents. The extract exhibited strong antioxidant capacity, particularly in the phosphomolybdenum assay (713.51 mg TEs/g), and showed notable radical scavenging activity in ABTS (140.00 mg TEs/g) and DPPH (99.20 mg TEs/g) assays. In H

Indexed as

AntioxidantsCellular SenescenceCollagenMatrix Metalloproteinase 1Matrix Metalloproteinase 3Oxidative StressPlant ExtractsSalviaCells, CulturedCell SurvivalFibroblastsHumansHydrogen PeroxideMolecular Docking SimulationAntioxidantsCollagenHydrogen PeroxideMatrix Metalloproteinase 1Matrix Metalloproteinase 3Plant ExtractsADMETgene expressionMM/GBSAmolecular dockingSalvia cadmicasenescence

Identifiers

PMID42571699
PMCPMC13453181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.