ArticleChemistry & biodiversity2026
Synthesis of Some Oxime Derivatives as Novel Elastase Inhibitors: Molecular Dynamics Studies and Computational Insight.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Oximes and oxime ethers are important compounds in organic chemistry, both structurally and in terms of applications. The biological properties of oximes are directly related to the chemical properties of their functional groups, metal-binding capacities, and ability to interact with biological targets in a multifaceted way. This study presents the synthesis of 5-hydroxyimino 2a-b and 5-methoxyimino 2c derivatives from 5-oxo pentanoic acid methyl esters (1a-c) containing phenyl, p-chlorophenyl, and thiophenyl groups, elucidation of their structures through various spectroscopic analysis methods (IR,
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