Evidence map›Paper›PMID 42571480›Full record

ArticleJournal of biomedical optics2026

Pigmentation-dependent skin injury thresholds with nanosecond single-pulse laser exposure.

Junior Arroyo, Jiaxin Zhang, Madhavi Tripathi, Junhao Zhang, Nethra Venkatayogi, Jamie Enslein, Muyinatu A Lediju Bell

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junior ArroyoJohns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland, United States.ORCID https://orcid.org/0000-0002-1752-4754
Jiaxin ZhangJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, Maryland, United States.ORCID https://orcid.org/0009-0005-4514-925X
Madhavi TripathiJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, Maryland, United States.
Junhao ZhangJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, Maryland, United States.ORCID https://orcid.org/0009-0001-0552-6082
Nethra VenkatayogiJohns Hopkins University, Department of Computer Science, Baltimore, Maryland, United States.
Jamie EnsleinJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, Maryland, United States.ORCID https://orcid.org/0009-0004-9532-2527
Muyinatu A Lediju BellJohns Hopkins University, Department of Biomedical Engineering, Baltimore, Maryland, United States.ORCID https://orcid.org/0000-0002-8394-4482

Funding

Photoacoustic Image Guidance of HysterectomiesR01EB032358 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Muyinatu A. Lediju Bell · 2023 to 2026
$1.5M
NIBIB NIH HHS R01 EB032358
6 · The paper itself

Abstract

Significance: Maximum permissible exposure limits defined in ANSI Z136.1 are broadly protective, but they do not explicitly account for pigmentation differences in skin. As a result, the lack of experimental data quantifying the effect of pigmentation on injury thresholds constrains accurate interpretation when melanin is a primary optical absorber, which has direct implications for the performance of optics-based imaging methods. Aim: We experimentally determined the pigmentation-dependent laser exposure dose that produces a visible injury in 50% of exposed sites (i.e., Approach: Fifty total abdominal skin sites per swine were identified on three swine with different pigmentation phenotypes (median ITA values per swine ranged Results: Dark-skinned swine ( Conclusions: The measured differences in

Indexed as

LasersSkinSkin PigmentationAnimalsColorimetryErythemaMelaninsSwineMelaninsindividual typology anglelaser safetylaser-tissue interactionpigmentationskin injury threshold

Identifiers

PMID42571480
PMCPMC13452404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.