Evidence map›Paper›PMID 42571405›Full record

ArticleBrain & spine2026

Subjective and objective cervical spine mobility after two-level anterior cervical discectomy and fusion - A prospective observational trial.

M Hohenhaus, M Bissolo, S Behringer, F Volz, R Watzlawick, J Beck, J-H Klingler, U Hubbe, C Scholz

Abstract read
In one paragraph

Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

M HohenhausDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
M BissoloDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
S BehringerDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
F VolzDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
R WatzlawickDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
J BeckDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
J-H KlinglerDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
U HubbeDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
C ScholzDepartment of Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cervical spine mobility is an important functional outcome following surgical procedures. For single-level ACDF, several studies indicated that cervical range-of-motion is not compromised and may even improve, despite fusion of the treated segment. Research question: This study investigates the cervical mobility for two-level ACDF. Material and methods: Prospective, observational trial on patients prior, 3 months and 1 year after degenerative two-level ACDF concerning objective goniometric and subjective quality of their cervical range-of-motion. Pain courses for neck and arm, quality of life (SF-8, ADLs) and patient satisfaction were queried. Results: 69 patients were analyzed (56.7 ± 11.0 years, 66.7% male). Goniometric range-of-motion worsened 3 months postoperatively in flexion-extension -11.5° (p < 0.001), lateral tilt -8.0° (p < 0.001) and rotation -3.6° (p = 0.062), regaining similar mobility to preoperative after 1 year (-1.5°, p = 0.700; -0.7°, p = 0.700; +2.9°, p = 1.000). Subjective range-of-motion improved significant after 3 months, and this improvement persisted even after 1 year. There was significant pain reduction at rest (NRS neck -1.2, p = 0.007; arm -2.0, p < 0.001) and under strain (NRS neck -1.5, p < 0.001; arm -2.9, p < 0.001) already after 3 months. Physical (+8.6, p < 0.001) and mental (+7.7, p = 0.065) component of SF-8 was improved and 92.8% were satisfied with the surgery. Conclusion: Two-level ACDF was not associated with deterioration in cervical spine mobility. Objective range-of-motion was temporarily reduced, returning to baseline after 1 year. Subjective mobility was already improved 3 months after surgery, accompanied by sustained pain reduction and improved quality of life. Consequently, concerns about postoperative motion reduction after two-level ACDF can be actively addressed.

Indexed as

ACDFAnterior cervical discectomy and fusionCervical mobilityCervical range of motionDegenerative cervical myelopathySpinal stenosis

Identifiers

PMID42571405
PMCPMC13452230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.