Evidence map›Paper›PMID 42571330›Full record

ArticleiScience2026

Myeloid-derived suppressor cells mitigate inflammation in periodontal disease.

Raza Ali Naqvi, Araceli Valverde, Salvador Nares, Thomas E Van Dyke, Afsar R Naqvi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raza Ali NaqviDepartment of Periodontics, University of Illinois Chicago, Chicago, IL 60612, USA.
Araceli ValverdeDepartment of Periodontics, University of Illinois Chicago, Chicago, IL 60612, USA.
Salvador NaresDepartment of Periodontics, University of Illinois Chicago, Chicago, IL 60612, USA.
Thomas E Van DykeDepartment of Applied Oral Sciences, The ADA Forsyth Institute, Cambridge, MA 02115, USA.
Afsar R NaqviDepartment of Periodontics, University of Illinois Chicago, Chicago, IL 60612, USA.

Funding

Human Herpesvirus Impact on Periodontal InflammationR01DE027980 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAQVI, AFSAR RAZA · 2018 to 2022
$1.9M
Functional Modulation of Myeloid Inflammatory Cells by miRNAR01DE021052 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NARES, SALVADOR · 2011 to 2015
$1.9M
Elucidating the novel regulatory role of long non-coding RNAs in myeloid inflammatory cell differentiation and functionR03DE027147 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAQVI, AFSAR RAZA · 2018 to 2019
$320k
NIDCR NIH HHS R01 DE021052NIDCR NIH HHS R01 DE027980NIDCR NIH HHS R03 DE027147
6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) are immature, immunosuppressive myeloid cells whose role in periodontal disease (PD) is not well defined. Here, we show that gingiva from PD patients exhibit increased infiltration of MDSCs, including granulocytic (G-MDSC) and monocytic (M-MDSC) subsets, alongside elevated CD4

Indexed as

inflammationMDSCsmyeloid-derived suppressor cellsPDperiodontal diseaseT regulatory cells

Identifiers

PMID42571330
PMCPMC13451856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.