ArticleCureus2026
Unilateral Lower Limb Edema as an Atypical Presentation of Thyrotoxicosis: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Peripheral edema in thyrotoxicosis is uncommon and is typically associated with cardiac dysfunction. Unilateral edema without overt heart failure is rarely reported. We present the case of a 40-year-old female patient who presented with edema involving the right lower limb and suprapubic and genital regions. Investigations revealed thyrotoxicosis associated with atrial fibrillation (AF). The patient demonstrated significant clinical improvement following treatment with antithyroid therapy, beta-blocker, glucocorticoids, and supportive management. This case highlights the importance of considering thyroid dysfunction in the differential diagnosis of unexplained unilateral edema after exclusion of more common vascular, infectious, and systemic causes.
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