Evidence map›Paper›PMID 42570106›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

What is the minimum effective wearing dosage of orthotic intervention in adolescent idiopathic scoliosis?

Shan Liu, Babak Hassan Beygi, Kenny Yat Hong Kwan, Shihan Li, Changliang Luo, Linjing Shang, Lejun Zhou, Wing Cheung Yeng, Man Sang Wong

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Shan LiuDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Babak Hassan BeygiDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Kenny Yat Hong KwanDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China.
Shihan LiDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Changliang LuoDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Linjing ShangDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Lejun ZhouDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Wing Cheung YengProsthetic and Orthotic Department, Duchess of Kent Children's Hospital, Hong Kong, China.
Man Sang WongDepartment of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China. m.s.wong@polyu.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to estimate the minimum effective orthosis-wearing time (MEWT) needed to prevent curve progression and reduce surgical risk in adolescent idiopathic scoliosis (AIS).

methodsThis retrospective study analyzed 281 patients with AIS who completed orthotic treatment. Compliance was measured using both objective temperature sensors and subjective self-reports, categorized into four daily wear-time levels: 0 to 6, 6 to 12, 12 to 18, and 18 to 24 h. Treatment outcomes at endpoint were classified as improvement (> 5° decrease), stabilization (± 5°), deterioration (> 5° increase), or surgical deterioration (Cobb angle > 50° or requiring surgery). Associations between compliance and outcomes were examined, and MEWT thresholds were estimated within risk-stratified subgroups based on baseline clinical risk factors.

resultsPatients wearing orthoses for 0 to 6 and 6 to 12 h/day showed significantly lower improvement rates and higher deterioration rates than those in the 12 to 18 and 18 to 24 h/day groups. No significant differences in treatment outcomes were observed between the 12 to 18 and 18 to 24 h/day groups, nor between the 0 to 6 and 6 to 12 h/day groups. Risk-stratified logistic regression models showed that MEWT estimates for curve deterioration ranged from 9.3 to 21.6 h/day, depending on target risk (20% to 5%) and Risser sign. For surgical deterioration, MEWT estimates at the 5% target risk ranged from 8.1 to 20.6 h/day. However, for patients with Risser 0 and a baseline Cobb angle > 30°, the model-derived MEWT estimates for target risks of 2% or lower exceeded 24 h/day and were therefore considered clinically infeasible.

conclusionsAlthough orthosis wear of 12 h per day or more was associated with better outcomes in group-level comparisons, MEWT is not uniform and varies by baseline clinical risk factors. Integrating objective compliance monitoring with risk-adapted targets may support personalized orthotic prescriptions, facilitate shared decision-making, and optimize treatment effectiveness.

Indexed as

Adolescent Idiopathic ScoliosisBrace ComplianceCurve ProgressionDose–Response RelationshipObjective MonitoringSpinal Orthosis

Identifiers

PMID42570106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.