Evidence map›Paper›PMID 42570101›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Kyphosis, lordosis and height velocity. What is the effect of rate of growth on the development of the sagittal parameters of the spine in normal children?

Adrian Gardner, Fiona Berryman, Paul Pynsent

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adrian GardnerAston Medical School, Aston University, Birmingham, UK. a.gardner2@aston.ac.uk.
Fiona Berryman
Paul Pynsent

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the effect of the rate of growth in standing height in the development of kyphosis and lordosis of normal children.

methodsAnalysis of the sagittal parameters of spinal shape from longitudinally collected ISIS2 surface topography measures were analysed alongside measures of standing height by comparing height velocity and the development of kyphosis and lordosis using linear mixed effects modelling techniques.

resultsThere were 831 measures from 196 children (79 females) between 2010 and 2017 aged between 9 and 18 years of age. Height velocity was between 0 and 12 cm/yr. There was a decrease in both kyphosis and lordosis for females as height velocity increased from 0 to 4 cm/yr whereon the measure plateaued. For males, kyphosis showed less change over all values of height velocity whereas lordosis had some variation between 5 and 6 cm/yr. There was a statistically significant difference between the sexes for lordosis (p = 0.02) but not for kyphosis (p = 0.07).

conclusionThe development of the sagittal shape of the spine is dependent on height velocity, and the effects of this differ between the sexes. This adds to the knowledge about the development of the shape of the spine along with informing future research into the aetiology of scoliosis.

trial registrationNational Research Ethics Service UK, NRES committee West MidlandsSouth Birmingham (11/H1207/10) awarded in 29/3/2011.

Indexed as

GrowthHeight velocityISIS2KyphosisLordosisSpine

Identifiers

PMID42570101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.