Evidence map›Paper›PMID 42570069›Full record

ArticleActa neurologica Belgica2026

Recurrent ischemic strokes with normal inflammatory markers: when tests mislead.

Isabel Ros González, Daniel Pérez Gil, Leticia Martín Gil, María Alexandra Figueroa Arenas, Oscar Fontsere Paton, Cristina Hormigos Martín, Sara Torrico Hatami, Manuel De La Calle Cuevas

Abstract read
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Article in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabel Ros GonzálezNeurology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain. isabelros95@hotmail.com.ORCID http://orcid.org/0009-0008-4899-5429
Daniel Pérez GilNeurology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
Leticia Martín GilNeurology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
María Alexandra Figueroa ArenasNeurology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
Oscar Fontsere PatonRheumatology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
Cristina Hormigos MartínRheumatology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
Sara Torrico HatamiPathology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.
Manuel De La Calle CuevasNeurology Department, Hospital Infanta Elena, Valdemoro, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell arteritis (GCA) is an uncommon cause of ischemic stroke, and diagnosis may be particularly challenging when inflammatory markers remain normal. We describe a 67-year-old woman with recurrent ischemic strokes preceded by new-onset headache. Neuroimaging showed bilateral severe stenosis of the distal intracranial internal carotid arteries, while temporal artery ultrasound and biopsy confirmed GCA. Recurrent cerebrovascular events occurred despite glucocorticoids and tocilizumab, requiring rescue therapy with cyclophosphamide, which achieved disease stabilization. This case illustrates an aggressive intracranial phenotype of GCA in which diagnosis and treatment decisions relied on clinical and imaging findings rather than inflammatory markers alone.

Indexed as

C-reactive proteinErythrocyte sedimentationGiant cell arteritisIschemic stroke

Identifiers

PMID42570069

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.