Evidence map›Paper›PMID 42569773›Full record

ArticleCureus2026

Severe Sepsis in an Adolescent With a De Novo Variant in the EP300 Gene Associated With Rubinstein-Taybi Syndrome Type 2: A Case Report.

Adriana Pinheiro, Mariana Oliveira, Beatriz Gonçalves, Cláudia F Reis

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adriana PinheiroPediatric Medicine, Hospital do Santo Espírito da Ilha Terceira, Angra do Heroísmo, PRT.
Mariana OliveiraPediatrics, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, PRT.
Beatriz GonçalvesFamily Medicine, Centro de Saúde de Angra do Heroísmo, Angra do Heroísmo, PRT.
Cláudia F ReisGenetics, Unidade Local de Saúde de Santo António, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rubinstein-Taybi syndrome type 2 (RSTS2) results from pathogenic variants in the

Indexed as

de novo variantfamily segregationintellectual developmental disorderrubinstein-taybi syndrome type 2severe infection

Identifiers

PMID42569773
PMCPMC13450703

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.