ArticleMacromolecules2021
Physical Property Scaling Relationships for Polyelectrolyte Complex Micelles.
Article in Macromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Ultrastable Water-in-Water Emulsions by Addition of Polyion Complex Micelles.Macromolecular rapid communications · 2026Article
- Composite biomaterials of polyelectrolyte complex micelle nanoparticles in hyaluronic acid gels enable local, targeted miR-92a inhibition and enhanced angiogenesis in diabetic wound repair.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- Effect of Polymer Structure on the Thermodynamics of Polyelectrolyte Complex Micelle Formation.Macromolecules · 2026Article
- Electrostatic Self-Assembly of Protein Nanoparticles from Intrinsically Disordered Polypeptide and Globular Protein Pairs.bioRxiv : the preprint server for biology · 2026Article
- Polyelectrolyte complex micelles embedded in hyaluronic acid gels enable local, targeted miR-92a inhibition to accelerate diabetic wound repair.bioRxiv : the preprint server for biology · 2025Article
- From Nano to Micro Polyion Complex Vesicles: Synthetic Cells with Membrane-Embedded Enzymes.ACS applied materials & interfaces · 2025Article
- Form Equals Function: Influence of Coacervate Architecture on Drug Delivery Applications.ACS biomaterials science & engineering · 2024Review
- Kinetically Controlled Polyelectrolyte Complex Assembly of microRNA-Peptide Nanoparticles toward Treating Mesothelioma.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Effect of Charged Block Length Mismatch on Double Diblock Polyelectrolyte Complex Micelle Cores.Macromolecules · 2023Article
- DNA dynamics in complex coacervate droplets and micelles.Soft matter · 2022Article
- Advances in the Structural Design of Polyelectrolyte Complex Micelles.The journal of physical chemistry. B · 2021Article
- Functional Nano-Objects by Electrostatic Self-Assembly: Structure, Switching, and Photocatalysis.Frontiers in chemistry · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Polyelectrolyte complex micelles (PCMs) are self-assembled nanoparticles formed by associative phase separation of hydrophilic neutral-charged block copolymers and polyelectrolytes and are effective in the delivery of hydrophilic payloads. Their attractive features include an ability to tune physical attributes such as core and corona size, particle shape, and stability, all of which are strongly dependent on the size and chemical structure of each polymer block. Previous studies have provided qualitative examples of these dependencies, but no quantitative structure-property relations have been developed to allow rational design of PCMs. Developing such design rules is crucial for applications and provides a greater understanding of the physics of polyelectrolyte assembly. In this work, we use small-angle X-ray scattering, electron microscopy, and light scattering to determine the scaling behavior of physical micelle parameters for commonly used, biologically relevant polyelectrolytes. As an example, for PCMs constructed from hydrophilic neutral-polyelectrolyte block copolymers and oppositely charged homopolymers, we find that the size of the PCM core increases strongly with the chain length of the polyelectrolyte block (∝
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.