ArticleJournal of oral and maxillofacial pathology : JOMFP
Crosstalk between salivary citrullinated proteins and oral health status in patients with rheumatoid arthritis: A cross-sectional study.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Context: Rheumatoid arthritis (RA) is often associated with reduced salivary flow, increasing susceptibility to opportunistic oral infections. Evidence suggests shared pathogenic mechanisms between RA and periodontitis. As a non-invasive medium, saliva offers potential for evaluating associations between anti-citrullinated protein antibody, Aims: To measure salivary citrullinated proteins in RA patients, detect Settings and Design: Cross-sectional study including 21 RA patients and 21 age- and gender-matched healthy controls. Materials and Methods: Unstimulated saliva was collected for citrullinated protein estimation using enzyme-linked immunosorbent assay and cultured on Sabouraud dextrose agar for Statistical Analysis Used: Mann-Whitney test, Chi-square, the Independent Student Results: Salivary citrullinated proteins showed significant positive correlation with Conclusions: Although not a standalone diagnostic marker, salivary citrullinated proteins correlate with microbial load and caries, supporting saliva-based biomarkers for RA monitoring.
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