ArticlePeerJ2026
Evaluation of sealing ability and adaptability of different endodontic sealers:
Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Root canal sealers play a critical role in preventing microleakage and ensuring the long-term success of endodontic treatment. AH-Plus is widely considered the gold standard epoxy resin-based sealer, while Bio-C sealer represents a newer premixed bioceramic material with bioactive properties. NanoSeal-S is a recently introduced silicone-based sealer reinforced with nanosilver particles, for which limited independent scientific data are currently available. Therefore, this study aimed to evaluate and compare the sealing ability and adaptability of these three root canal sealers. Materials and Methods: Forty-five extracted single-rooted human teeth were decoronated and randomly divided into three experimental groups ( Results: NanoSeal-S showed the highest interfacial contact percentage (92.3%), followed by AH-Plus (75.8%) and Bio-C sealer (59.9%), with a statistically significant difference ( Conclusion: NanoSeal-S demonstrated superior interfacial adaptability, whereas Bio-C sealer showed the least microleakage among the tested materials.
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