Evidence map›Paper›PMID 42569364›Full record

ArticleAging brain2026

Effects of aerobic exercise intervention on the association between brain functional connectivity and cognition among older adults.

Myungjin Jung, Marco Pipoly, Bryan Madero, Chris Oehler, Kelsey Baller, Vincent A Magnotta, Jeffrey D Long, Gary L Pierce, Michelle W Voss

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging brain, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Myungjin JungDepartment of Kinesiology, Health Promotion and Recreation, University of North Texas, Denton, TX 76201, USA.
Marco PipolyDepartment of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA.
Bryan MaderoDepartment of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA.
Chris OehlerDepartment of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA.
Kelsey BallerDepartment of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA.
Vincent A MagnottaDepartment of Radiology, The University of Iowa, Iowa City, IA 52242, USA.
Jeffrey D LongDepartment of Psychiatry, The University of Iowa, Iowa City, IA 52242, USA.
Gary L PierceDepartment of Health and Human Physiology, The University of Iowa, Iowa City, IA 52242, USA.
Michelle W VossDepartment of Psychological and Brain Sciences, The University of Iowa, Iowa City, IA 52242, USA.

Funding

Exercise to improve hippocampal connectivity and learning in older adultsR01AG055500 · NIA · UNIVERSITY OF IOWA · PI VOSS, MICHELLE WEBB · 2017 to 2021
$3.5M
University of Iowa - Research 3T MRI Connectome UpgradeS10OD025025 · OD · UNIVERSITY OF IOWA · PI MAGNOTTA, VINCENT A · 2018 to 2018
$1.9M
NIA NIH HHS R01 AG055500NIH HHS S10 OD025025
6 · The paper itself

Abstract

Chronic aerobic exercise is known to protect against brain and cognitive aging in animals, but it remains unclear whether these benefits are consistent across the span of older adulthood. Using time-varying effect modeling (TVEM) analysis, this study investigated how the associations between changes in cognition and brain network functional connectivity (FC), induced by a 6-month aerobic exercise intervention, vary with age among older adults aged 55 to 80 (

Indexed as

Cognitive performanceNeural networkPhysical activityResting state fMRITime-varying effect modeling

Identifiers

PMID42569364
PMCPMC13450027

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.