ArticleMolecular therapy. Advances2026
Double activation and low IL-2 manufacturing protocol increase expansion of healthy and patient-derived CAR-Tregs.
Article in Molecular therapy. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
Chimeric antigen receptor (CAR)-engineered regulatory T cells (CAR-Tregs) are a promising approach to restore immune tolerance in autoimmune diseases (ADs). However, the low frequency of circulating Tregs, especially in patients with autoimmunity, might limit their applicability as a clinical approach. Thus, an optimal protocol for
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