Evidence map›Paper›PMID 42569178›Full record

ArticleOpen life sciences2026

Darutoside ameliorates adjuvant-induced arthritis in mice by repolarizing M1/M2 macrophages through inhibition of JAK2-STAT3-p65 signaling pathway.

Jun Wang, Shiya Gao, Mingsong Meng, Zilin Zhang, Sen Zhang, Jing Han, Dongsheng Wang

Abstract read
In one paragraph

Article in Open life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun WangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Shiya GaoSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Mingsong MengSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zilin ZhangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Sen ZhangSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jing HanSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Dongsheng WangDepartment of Spine Surgery, Center of Orthopedics, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing Key Laboratory of Spinal Disease Therapy and Regeneration (Military-Civilian), Chongqing, 400042, China.ORCID https://orcid.org/0000-0001-7312-9612

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Darutoside (DA), a diterpenoid compound derived from

Indexed as

darutosideJAK2-STAT3macrophagesrheumatoid arthritis

Identifiers

PMID42569178
PMCPMC13449442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.