Evidence map›Paper›PMID 42569120›Full record

ArticlePhysics and imaging in radiation oncology2026

Helium pencil beam commissioning and beam modeling.

Lukas Martin, Barbara Knäusl, Peter Kuess, Dietmar Georg, Hugo Palmans, Lorenz Wolf, Nadia Gambino, Fabio Farinon, Andrej Prochazka, Mansure Schafasand and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lukas MartinMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Barbara KnäuslMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Peter KuessMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Dietmar GeorgMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Hugo PalmansMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Lorenz WolfMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Nadia GambinoMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Fabio FarinonMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Andrej ProchazkaMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Mansure SchafasandMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Lars GlimeliusRaySearch Laboratories AB, Eugeniavägen 18C, Stockholm, 113 68, Sweden.
Walter Ikegami AnderssonRaySearch Laboratories AB, Eugeniavägen 18C, Stockholm, 113 68, Sweden.
Daniel Simon ColomarRaySearch Laboratories AB, Eugeniavägen 18C, Stockholm, 113 68, Sweden.
Antonio CarlinoMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Markus StockMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.
Hermann FuchsMedAustron Ion Therapy Center, Marie Curie-Straße 5, Wiener Neustadt, A-2700, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Helium ions combine reduced lateral scattering compared to protons and a lower fragmentation tail than carbon ions, enabling sharp dose gradients and improved normal tissue sparing. This study reports the commissioning of a scanned helium pencil beam line and validation of its corresponding beam model. Materials and Methods: Synchrotron-based helium ion beams were commissioned covering energies from 54.6 to 402.8 MeV/u. Depth-dose curves were measured and absolute dose calibration was performed. Beam optics (spot size, position, and intraspill stability) were evaluated for various spill lengths. A beam model was implemented in the RayStation treatment planning system (TPS) and validated through 2D absolute dose measurements in homogeneous and heterogeneous phantoms and 3D measurements of cubic spread-out Bragg peak fields. Gamma-index analysis and Monte Carlo (MC) simulations with GATE/Geant4 were performed for benchmarking. Results: Measured ranges agreed with MC simulations within Conclusions: Stable scanned beam delivery with helium ions was established. Validation demonstrated strong agreement between measurements, TPS calculations, and MC simulations, supporting research and future clinical application.

Indexed as

Beam commissioningDosimetryHelium ion therapyMonte Carlo simulationParticle therapy

Identifiers

PMID42569120
PMCPMC13449418

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.