Evidence map›Paper›PMID 42568805›Full record

ArticlePNAS nexus2026

ENaC phosphorylation facilitates ankyrin-3 interaction critical for renal sodium balance.

Tarek Mohamed Abd El-Aziz, Antonio G Soares, Elena Mironova, Crystal R Archer, Amr Setouhi, Brij B Singh, James D Stockand

Abstract read
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tarek Mohamed Abd El-AzizCenter for Regenerative Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID https://orcid.org/0000-0002-3441-9673
Antonio G SoaresPacific Biosciences Research Center, University of Hawai'i at Mānoa, Honolulu, HI 96848, USA.ORCID https://orcid.org/0000-0001-5814-3475
Elena MironovaGreehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID https://orcid.org/0000-0002-2579-5319
Crystal R ArcherDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.ORCID https://orcid.org/0000-0002-2377-643X
Amr SetouhiCardiology Department, Faculty of Medicine, Minia University, El-Minia 61519, Egypt.
Brij B SinghCenter for Regenerative Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID https://orcid.org/0000-0003-0535-5997
James D StockandDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

Funding

Training in Cardiovascular Research at the University of HawaiiT32HL115505 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI Michelle D Tallquist · 2012 to 2026
$3.8M
Purinergic regulation of ENaC in the distal nephronR01DK113816 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI STOCKAND, JAMES D · 2018 to 2021
$1.4M
Regulation of ENaC by Casein Kinase 2R01DK117909 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI STOCKAND, JAMES D · 2018 to 2021
$1.4M
NHLBI NIH HHS T32 HL115505NIDDK NIH HHS R01 DK113816NIDDK NIH HHS R01 DK117909
6 · The paper itself

Abstract

Kidneys play a pivotal role in long-term blood pressure regulation by controlling extracellular fluid volume through renal salt reabsorption. Discretionary control of the Epithelial Na

Indexed as

casein kinaseepithelial sodium channelphosphorylationsalt-sensitive hypertensionsodium reabsorption

Identifiers

PMID42568805
PMCPMC13447671

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.