Evidence map›Paper›PMID 42568781›Full record

ReviewPalliative care and social practice2026

Contexts, mechanisms and outcomes of home-based palliative care implementation in low- and middle-income countries: A realist review.

Duong Dai Le, Khoa Duy Duong, Anna Peeler, Mevhibe Hocaoglu, Charles Normand, Irene Higginson, Richard Harding

Abstract readReview
In one paragraph

Review in Palliative care and social practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Duong Dai LeDepartment of Medical Ethics - Social Medicine - Palliative Care, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0002-3048-9180
Khoa Duy DuongInstitute of Health Sciences Education, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada.
Anna PeelerCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Mevhibe HocaogluCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Charles NormandCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Irene HigginsonCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.
Richard HardingCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.ORCID https://orcid.org/0000-0001-9653-8689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In 2015, an estimated 16.4 million people in low-and-middle-income countries (LMICs) died with serious health-related suffering requiring palliative care. Yet access to palliative care remains limited in LMICs, where the gaps are greatest. Home-based palliative care (HBPC) has been shown to improve access, enhance quality of life and reduce costs. However, evidence on implementing HBPC across the diverse contexts of LMICs remains scarce. Aim: To identify which strategies, in which contexts, trigger which mechanisms to produce successful implementation outcomes for HBPC in LMICs. Data sources and Methods: Following RAMESES standards, we conducted a realist review to refine an initial programme theory developed through WHO documentation and the CFIR. We searched six databases (MEDLINE, PsycINFO, CINAHL, EMBASE, Global Health, and CENTRAL) for home-based palliative care in LMICs. Evidence was selected based on relevance, richness, and rigour, using 17 "if-then" statements to synthesise Context-Mechanism-Outcome-Configurations (CMOCs). Results: In LMICs, patients with advanced illness and caregivers experience substantial multidimensional unmet needs within health systems that are underfunded and fragmented. We identified five CMOCs in which HBPC was found to be acceptable, feasible, and sustainable. (1) Community engagement: Programmes that actively engaged community members and local civil organisations reduced stigma surrounding palliative care, strengthened collective ownership, and improved programme acceptability and sustainability. (2) Volunteer involvement: Training community-rooted caregivers created trusted bridges between services and families, enhancing volunteer commitment and long-term viability. (3) Nurse leadership: Empowering nurses through training and expanded roles increased professional confidence and trust from patients and families, supporting delivery in resource-constrained settings. (4) Multidisciplinary team: Collaborative team care alleviated feelings of abandonment, fostered hope and reciprocity; encouraged patients and families to contribute back to programmes. (5) Holistic and uninterrupted support for caregivers: Continuous and holistic support for family carers improved confidence in home caregiving and enabled end-of-life care at home. Conclusion: Shared contextual similarities across LMICs suggest these components could support HBPC implementation in diverse resource constrained settings and potential for cross-national learning. To maximise successful implementation, investment for HBPC should prioritise enhancing community capacity and developing nurse leadership within the team care model.

Indexed as

home-based palliative careimplementation scienceLMICrealist reviewrealist synthesis

Identifiers

PMID42568781
PMCPMC13447999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.