ArticleFrontiers in medicine2026
COVID-19 vaccination rates as a proxy for health system resilience: implications of development disparities for cervical cancer control during the pandemic.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To assess COVID-19's impact on global cervical cancer burden and examine how COVID-19 vaccination rates and Human Development Index (HDI) interact to shape disease trends, with exploratory projections to 2050. Methods: Using Global Burden of Disease 2023 data (1990-2023), we analyzed age-standardized incidence (ASIR) and disability-adjusted life-year (DALY) rate of cervical cancer. Joinpoint regression estimated annual percentage changes (EAPC) for pre-pandemic (1990-2019) and pandemic (2020-2023) periods. Linear and interaction models assessed associations between HDI, COVID-19 vaccination rates, and EAPC, with bidirectional stratified analyses. Projections to 2050 were generated under three exploratory scenarios. Results: The pandemic coincided with a reversal of the pre-pandemic declining trend in cervical cancer burden indicators. Global ASIR increased 6.0% ( Conclusion: COVID-19 vaccination rate shows context-dependent associations with cervical cancer burden: stronger negative associations in low-HDI settings and positive associations in high-HDI settings. These findings support dual-purpose investments in emergency infrastructure for pandemic preparedness and cancer control.
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