Evidence map›Paper›PMID 42568555›Full record

ArticleFrontiers in bioengineering and biotechnology2026

A personalized simulation framework for optimizing orthokeratology lens parameters based on 3D corneal modeling and biomechanical analysis.

Qi-Ou Chen, Enxu Peng, Gaiping Zhao, Ping Ye, Zhaohua Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi-Ou ChenSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Enxu PengCollege of Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Gaiping ZhaoSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Ping YeSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Zhaohua ChangSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to develop a patient-specific finite element model (FEM) to elucidate the biomechanical mechanisms governing orthokeratology (OK) lens design in real ocular conditions. Based on clinical corneal topography data, a patient-specific FEM was developed to incorporate asymmetric anatomical features. This model integrated an improved Iterative Closest Point (ICP) algorithm and a non-uniform squeeze-film pressure field. Simulation results were then compared with clinical measurements across multiple dimensions to evaluate predictive accuracy. The simulation framework demonstrated high predictive fidelity, The average Structure Similarity Index

Indexed as

biomechanicsfinite element analysislens designmyopia controlorthokeratologytear squeeze film

Identifiers

PMID42568555
PMCPMC13447291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.