Evidence map›Paper›PMID 42568412›Full record

ArticleFrontiers in endocrinology2026

Recombinant LH priming improves follicular efficiency and pregnancy outcomes in women with diminished ovarian reserve undergoing antagonist IVF stimulation.

Diletta Guglielmi, Claudio Maurizio Maria Brigante, Silvana Gippone, Roberta Iemmello, Mariabeatrice Dal Canto, Mario Romano Mignini Renzini

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diletta GuglielmiBiogenesi, Reproductive Medicine Centre, Monza, Italy.
Claudio Maurizio Maria BriganteBiogenesi, Reproductive Medicine Centre, Monza, Italy.
Silvana GipponeBiogenesi, Reproductive Medicine Centre, Monza, Italy.
Roberta IemmelloBiogenesi, Reproductive Medicine Centre, Monza, Italy.
Mariabeatrice Dal CantoBiogenesi, Reproductive Medicine Centre, Monza, Italy.
Mario Romano Mignini RenziniBiogenesi, Reproductive Medicine Centre, Monza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with diminished ovarian reserve represent a low-prognosis population in assisted reproduction, in whom improving the efficiency of converting the available antral follicle pool into retrievable oocytes may be clinically relevant. We conducted a retrospective single-center cohort study including 232 IVF/ICSI cycles (232 women) performed between January 2022 and April 2025 in POSEIDON groups 3-4 (anti-Müllerian hormone <1.2 ng/mL), comparing a high-dose antagonist regimen preceded by combined oral contraceptive pretreatment plus recombinant luteinizing hormone priming (150 IU/day for 7 days; LHP,

Indexed as

Fertilization in VitroLuteinizing HormoneOvarian FollicleOvarian ReserveOvulation InductionAdultFemaleFollicle Stimulating HormoneHumansOocyte RetrievalPregnancyPregnancy OutcomePregnancy RateRecombinant ProteinsRetrospective StudiesFollicle Stimulating HormoneLuteinizing HormoneRecombinant Proteinsdiminished ovarian reserveGnRH antagonistIVF/ICSIpoor ovarian responserecombinant luteinizing hormone

Identifiers

PMID42568412
PMCPMC13447135

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.