Evidence map›Paper›PMID 42568013›Full record

ReviewCardiovascular intervention and therapeutics2026

Understanding prosthesis patient mismatch in aortic valve replacement: from pitfalls to clinical impact.

Akihiro Tobe, Patrick W Serruys, Yoshinobu Onuma, Christian Juhl Terkelsen, Mads Jønsson Andersen, Michele Gallazzi, Angela McInerney, Scot Garg, Jose Luis Pomar

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiovascular intervention and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akihiro TobeCORRIB Research Centre for Advanced Imaging and Core laboratory, University of Galway, Galway, Ireland.
Patrick W SerruysCORRIB Research Centre for Advanced Imaging and Core laboratory, University of Galway, Galway, Ireland. patrick.w.j.c.serruys@gmail.com.ORCID http://orcid.org/0000-0002-9636-1104
Yoshinobu OnumaCORRIB Research Centre for Advanced Imaging and Core laboratory, University of Galway, Galway, Ireland.
Christian Juhl TerkelsenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Mads Jønsson AndersenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Michele GallazziDepartment of Medical and Surgical Sciences, Faculty of Medicine and Surgery, School of Cardiovascular Diseases, University of Milan, Milan, Italy.
Angela McInerneyDepartment of Cardiology, University Hospital Galway, Galway, Ireland.
Scot GargDepartment of Cardiology, Royal Blackburn Hospital, Blackburn, UK.
Jose Luis PomarThe Cardiovascular Institute Hospital Clinic & University of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Almost half a century ago, cardiac surgeons introduced the concept of prosthesis-patient mismatch (PPM), which was defined by indexing the effective orifice area (EOA) to body surface area. Although PPM has demonstrated strong prognostic value following surgical aortic valve replacement (SAVR), its significance in transcatheter aortic valve replacement (TAVR) remains uncertain. In this review, we revisit the concept of PPM and explore the methodological and clinical challenges in its application. Special focus is given to the limitations in interpreting EOA and indexed EOA (EOAi), including flow dependency and imaging variability. We also review the literature evaluating the association between PPM and clinical outcomes after SAVR and TAVR. Finally, we discuss a potential role of alternative metric such as the fitting index.

Indexed as

Aortic ValveAortic Valve StenosisHeart Valve ProsthesisHeart Valve Prosthesis ImplantationProsthesis FittingTranscatheter Aortic Valve ReplacementHumansProsthesis DesignAortic stenosisFitting indexProsthesis patient mismatchSurgical aortic valve replacementTranscatheter aortic valve replacement

Identifiers

PMID42568013
PMCPMC13582111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.