Evidence map›Paper›PMID 42568006›Full record

ArticleMolecular diversity2026

Rapid assembly of structurally diverse 3,4-dihydroquinazolines with anticancer activity via SDS-promoted aqueous synthesis.

Fu-Qiang Yu, Pei-Lu Song, Yan-Rui Fan, Jun-Wei Wang, Xu-Jie Wang, Jin-Fei Yang

Abstract read
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In one paragraph

Article in Molecular diversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fu-Qiang Yu *School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China.
Pei-Lu Song *School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China.
Yan-Rui FanSchool of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China.
Jun-Wei WangSchool of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China.
Xu-Jie WangSchool of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China. wangxujie@uhrs.edu.cn.ORCID https://orcid.org/0000-0001-6633-9670
Jin-Fei YangSchool of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, 266001, China. jfyang@uhrs.edu.cn.

Funding

National Natural Science Foundation of China 22501114National Natural Science Foundation of China 22507051Natural Science Foundation of Qingdao Municipality 24-4-4-zrjj-117-jchNatural Science Foundation of Qingdao Municipality 24-4-4-zrjj-162-jchNatural Science Foundation of Shandong Province ZR2025QC1356Taishan Scholar Project of Shandong Province tsqn202103108
6 · The paper itself

Abstract

A convenient SDS-promoted strategy enables the synthesis of a 42-member library of structurally diverse 3,4-dihydroquinazolines in an aqueous medium. The protocol features mild reaction conditions, operational simplicity, and facile scalability. Synthetic transformations highlight the versatility of the scaffold, while preliminary biological evaluation identifies compound 3v as a promising inhibitor against U87 glioblastoma cells.

Indexed as

3,4-dihydroquinazolinesAntitumor activityAqueous reactionMolecular diversitySDS-promoted synthesis

Identifiers

PMID42568006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.