Evidence map›Paper›PMID 42566522›Full record

ArticleScience advances2026

3D genome organization in tissue regeneration involves long-range chromatin loops.

Palmira Llorens-Giralt, Carlos Camilleri-Robles, Leo Zuber, Jenisha Khadka, Maria Marti-Marimon, Andrea Crespo-Pera, Florenci Serras, Maria Cristina Gambetta, Marc A Marti-Renom, Montserrat Corominas

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Palmira Llorens-GiraltDepartment of Genetics, Microbiology, and Statistics, School of Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.ORCID 0000-0002-1378-4647
Carlos Camilleri-RoblesDepartment of Genetics, Microbiology, and Statistics, School of Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.
Leo ZuberCentre Nacional d'Anàlisi Genòmica (CNAG), Barcelona, Catalonia, Spain.ORCID 0000-0002-4968-033X
Jenisha KhadkaCenter for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0009-0001-5282-9107
Maria Marti-MarimonCentre Nacional d'Anàlisi Genòmica (CNAG), Barcelona, Catalonia, Spain.ORCID 0000-0001-8162-2845
Andrea Crespo-PeraDepartment of Genetics, Microbiology, and Statistics, School of Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.
Florenci SerrasDepartment of Genetics, Microbiology, and Statistics, School of Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.
Maria Cristina GambettaCenter for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0002-9450-3551
Marc A Marti-RenomCentre Nacional d'Anàlisi Genòmica (CNAG), Barcelona, Catalonia, Spain.ORCID 0000-0002-0151-4279
Montserrat CorominasDepartment of Genetics, Microbiology, and Statistics, School of Biology, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Catalonia, Spain.ORCID 0000-0002-0724-8346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The three-dimensional (3D) organization of the genome plays a fundamental role in gene expression regulation, yet how changes in genome architecture influence transcriptional responses during tissue regeneration remains poorly understood. Here, we used Hi-C to profile 3D chromatin conformation during

Indexed as

ChromatinRegenerationAnimalsDrosophila melanogasterHistonesImaginal DiscsWings, AnimalChromatinHistones

Identifiers

PMID42566522
PMCPMC13450218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.