Evidence map›Paper›PMID 42566489›Full record

ArticlePLOS global public health2026

Resilience of health systems in Africa to infectious disease shocks: A qualitative evidence synthesis.

Denis Okethwangu, Sherry Ahirirwe, Mahima Venkateswaran, Roy Mayega, Elizeus Rutebemberwa, Felix Ocom, Victoria Nankabirwa, Charles L Okot, Evelyne B Nyachwo, Sandra Nabatanzi and 5 more

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Denis OkethwanguDepartment of Health Policy, Planning and Management, Makerere University School of Public Health, Kampala, Uganda.ORCID https://orcid.org/0000-0001-8421-6359
Sherry AhirirweUganda National Institute of Public Health, Ministry of Health, Kampala, Uganda.
Mahima VenkateswaranDepartment of Global Health, Norwegian Institute of Public Health, Oslo, Norway.ORCID https://orcid.org/0000-0002-1226-5685
Roy MayegaDepartment of Epidemiology and Biostatistics, Makerere University School of Public Health, Kampala, Uganda.
Elizeus RutebemberwaDepartment of Health Policy, Planning and Management, Makerere University School of Public Health, Kampala, Uganda.
Felix OcomUganda National Institute of Public Health, Ministry of Health, Kampala, Uganda.
Victoria NankabirwaDepartment of Epidemiology and Biostatistics, Makerere University School of Public Health, Kampala, Uganda.
Charles L OkotEpidemic Preparedness and Response Unit, World Health Organization Regional Office for Africa, Brazzaville, Congo.ORCID https://orcid.org/0000-0001-7313-207X
Evelyne B NyachwoDepartment of Disease Control and Environmental Health, Makerere University School of Public Health, Kampala, Uganda.
Sandra NabatanziDepartment of Epidemiology and Biostatistics, Makerere University School of Public Health, Kampala, Uganda.
Evelyn AsioDepartment of Epidemiology and Biostatistics, Makerere University School of Public Health, Kampala, Uganda.ORCID https://orcid.org/0009-0004-2067-988X
Umaer N MohammedDepartment of Global Health, Norwegian Institute of Public Health, Oslo, Norway.
Alex R ArioUganda National Institute of Public Health, Ministry of Health, Kampala, Uganda.
Frode ForlandDepartment of Global Health, Norwegian Institute of Public Health, Oslo, Norway.
Suzanne N KiwanukaDepartment of Health Policy, Planning and Management, Makerere University School of Public Health, Kampala, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong and resilient health systems are those equipped to withstand shocks and continue providing quality services as response measures are implemented. We conducted a qualitative evidence synthesis of stakeholders' understanding of health system resilience in Africa, focusing on definitions and attributes. We searched for peer-reviewed articles and grey literature, filtered for Africa, from 1980 to November 2025, using the SPIDER framework. The search was conducted in four databases: PubMed, the Bielefeld Academic Search Engine, the Cumulative Index to Nursing and Allied Health Literature, and Scopus; we also reviewed the websites of the World Health Organization (WHO), Africa Centers for Disease Control and Prevention (Africa CDC), and Ministries of Health of African countries. Articles were selected based on predefined inclusion and exclusion criteria. Qualitative articles were appraised using the Critical Appraisal Skills Programme, and mixed-methods articles using the Mixed Methods Appraisal Tool. We mapped the distribution of included articles by the country studied, the infectious disease responsible for the shock, and the health system building block described. For each article, we identified the definition of health system resilience and its attributes. The search yielded 5,448 relevant articles, eighty-three of which were included in the synthesis. Articles were from 48 of the 54 African countries. Up to 74.5% of the articles focused on COVID-19; others were on Ebola Virus Disease, cholera, and meningitis. Service delivery, leadership and governance and health workforce were the most frequently cited health system building blocks. Adaptive capacity of health systems resilience was most frequently cited, followed by absorptive capacity, preparedness, and recovery. Identified attributes of a resilient health system were community engagement and involvement; leadership and governance; collaborations and partnerships; human resources for health; health education and promotion; health information systems; health service delivery; decentralization and local governance; health infrastructure and logistics; preparedness; learning and adaptation; and innovation and financing.

Identifiers

PMID42566489
PMCPMC13450801

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.